Professor of Medicine
UT Health Mc Govern Medical School
Houston, Texas, United States
My research interest is in central nervous system infections. During my fellowship I obtained a NRSA award from the NINDS to evaluate the role of cranial imaging in adults with suspected meningitis. This study was published in the NEJM and was used by the IDSA in the Bacterial Meningitis clinical guidelines to rationalize the use of Head CT scan in patients with suspected meningitis. I joined the University of Texas in September 2008 and with funding from a K23 training grant and from the Grant A Star foundation we have enrolled over 1,500 adults and children with meningitis and encephalitis that have resulted in 56 publications. I have also obtained funding from the Baylor UT CFAR to study HIV associated neurocognitive disorders, and in collaboration with Dr. Woods from the University of Houston we have expanded these studies to evaluate the long-term neurocognitive sequelae of West Nile virus infection. I also served as a co-investigator of the U24-funded National Neuro AIDS Tissue Consortium that evaluate patients for neurocognitive disorders. I am also a co-investigator for an R01-funded study to evaluate the neuropathological and biochemical abnormalities observed in people living with HIV (PLWH) affected by HIV-associated neurocognitive disorder (HAND) in direct comparison with those observed in other neurodegenerative diseases (NDs), especially Alzheimer’s disease (AD). I have also been a co-investigator with Dr. Kristy Murray’s R01-funded West Nile cohort study where I helped organize a comprehensive neurological, ophthalmological, neurocognitive, and neuroradiological (volumetric and functional MRI) evaluation. I am a member of the international NeuroCOVID consortium and we are currently working on several encephalitis studies in collaboration with Arun Venkatesan's group at Hopkins. I am the author of two meningitis chapter in the Mandell Principles and Practice of Infectious Diseases and author of 5 meningitis chapters on UpToDate.
Disclosure(s): bioMerieux Inc.: Grant/Research Support (Ongoing), Honoraria (Ongoing)
16 - Progress and Challenges in the Management of CNS Infections
Thursday, October 17, 2024
8:00 AM – 9:00 AM US PT
49 - Review of Progress and Challenges in Bacterial Meningitis and Encephalitis
Thursday, October 17, 2024
8:00 AM – 8:30 AM US PT