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Sanjay K. Jain, MD

Professor
Johns Hopkins Children's Center
Baltimore, MD, United States

Sanjay K Jain, M.D. is Professor of Pediatrics, Radiology & Radiological Sciences and International Health at the Johns Hopkins University. He directs the Center for Infection and Inflammation Imaging Research and is a member of the Center for TB Research at Johns Hopkins. Dr. Jain is also the Vice Chair for Basic & Translational Research in the Department of Pediatrics. His primary research interests include the development of novel molecular imaging technologies for bacterial infections, pediatric tuberculosis (TB), and TB meningitis. Dr. Jain’s laboratory conducts animal and human studies to develop and evaluate novel radiopharmaceutical imaging methods (CT, PET, SPECT, MRI) to understand disease pathogenesis (e.g. study antimicrobial pharmacokinetics at infection sites) and pathogen-specific imaging diagnostics. Several novel tracers developed in his laboratory are now being tested in first-in-human studies. For example, they have performed first-in-human studies using a radiolabeled version of rifampin (an important antibiotic) in humans with TB or S. aureus infections to test whether rifampin achieves adequate levels at the infection sites. Similarly, his group has also evaluated a novel bacterial-specific PET tracer to noninvasively detect infections due to Enterobacterales in humans, the most common cause of Gram-negative bacterial infections in humans and a frequent cause of serious multidrug-resistant infections.

Dr. Jain is funded though several grants. Notably, he is also the recipient of the prestigious NIH Director’s New Innovator Award (2009) and the NIH Director’s Transformative Research Award (2014). Dr. Jain is the past chair (2014-2021) and a founding member of the Infectious Diseases subgroup and current board member of the World Molecular Imaging Society. He serves as a reviewer for multiple scientific journals and NIH study panels.

Disclosure(s): Fujirebio Diagnostics, Inc. (Malvern PA): Grant/Research Support (); Novobiotics, LLC: Advisor/Consultant (), Grant/Research Support (); T3 Pharmaceuticals (Basel, Switzerland): Grant/Research Support ()

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