87 - Machine Learning-Guided Generation of a Potent Combination of Broadly Neutralizing Sarbecovirus Antibodies with a High Barrier to Resistance

Thursday, October 17, 2024

10:30 AM – 10:42 AM US PT

Location: 411

Presenting Author(s)

KS

Kimberly Schmitt, PhD (she/her/hers)

Senior Scientist II
Generate:Biomedicines
Somerville, MA, United States

Slides

Co-Author(s)

GM

Grace Marden, MS

Senior Research Associate
Generate Biomedicines
Quincy, Massachusetts, United States

Co-Author(s)

EC

Eric Carlin, PhD

Scientist
Generate Biomedicines
Somerville, Massachusetts, United States

Co-Author(s)

AR

Alex Ramos, PhD

Associate Director, Machine Learning Operations
Generate Biomedicines
Wilbraham, Massachusetts, United States
HL

Hongru Li, PhD

Scientist
Generate Biomedicines
Brookline, Massachusetts, United States
NS

Nadine Shaban, PhD

Senior Scientist II
Generate Biomedicines
Sommerville, Massachusetts, United States
MM

Monica Menzenski, BS/MS

Generate Biomedicines
Somerville, Massachusetts, United States
GS

Geetika Sharma, Ph.D.

Scientist II
Generate Biomedicines
Boston, Massachusetts, United States
RF

Ross Federman, PhD

Generate Biomedicines
Sommerville, Massachusetts, United States
AL

Alan Leung, PhD

Director
Generate Biomedicines
Somerville, Massachusetts, United States
NL

Nicole Leon Vargas, Bachelor of Science in Biomedical Engineering

Generate Biomedicines
Somerville, Massachusetts, United States
BH

Brett T. Hannigan, PhD

Sr. Director Quantitative Biology
Generate Biomedicines
Broomfield, Colorado, United States
PR

Pamela Russell, MA

Generate Biomedicines
Denver, Colorado, United States
AR

Adam Root, MS, MBA

Generate Biomedicines
Somerville, Massachusetts, United States
HV

Heather A. Van Epps, PhD

Executive Director, Head of Therapeutic Research
Generate Biomedicines
Boston, Massachusetts, United States
KH

Kristen Hopson, Ph.D.

Generate Biomedicines
Lincoln, Massachusetts, United States
AP

Amarendra Pegu, PhD

Associate Director, Infectious Disease
Generate Biomedicines
Somerville, Massachusetts, United States
GG

Gevorg Grigoryan, PhD

Chief Technology Officer
Generate Biomedicines
Somerville, Massachusetts, United States
GK

Gavin CKW Koh, PhD

Executive Director
Generate:Biomedicines
Somerville, Massachusetts, United States
DH

Daria Hazuda, PhD

Head of Infectious Diseases
Generate Biomedicines
Henderson, Nevada, United States
Francesco Borriello, MD PhD (he/him/his)

Associate Director
Generate Biomedicines
Lexington, Massachusetts, United States

Disclosure(s):

Kimberly Schmitt, PhD: No financial relationships to disclose

Grace Marden, MS: No financial relationships to disclose

Eric Carlin, PhD: No financial relationships to disclose

Alex Ramos, PhD: Generate Biomedicines: Stocks/Bonds (Private Company)

Hongru Li, PhD: No financial relationships to disclose

Nadine Shaban, PhD: No financial relationships to disclose

Monica Menzenski, BS/MS: No financial relationships to disclose

Geetika Sharma, Ph.D.: No financial relationships to disclose

Ross Federman, PhD: No financial relationships to disclose

Alan Leung, PhD: Generate Biomedicines: Stocks/Bonds (Private Company)

Nicole Leon Vargas, Bachelor of Science in Biomedical Engineering: No financial relationships to disclose

Brett T. Hannigan, PhD: Generate Biomedicines: Employee, Stocks/Bonds (Private Company)

Pamela Russell, MA: No financial relationships to disclose

Adam Root, MS, MBA: Generate Biomedicines: Grant/Research Support, Stocks/Bonds (Private Company)

Heather A. Van Epps, PhD: Generate Biomedicines: Stocks/Bonds (Private Company)

Kristen Hopson, Ph.D.: Generate Biomedicines: Stocks/Bonds (Private Company)

Amarendra Pegu, PhD: No financial relationships to disclose

Gevorg Grigoryan, PhD: Generate Biomedicines, Inc.: Employee and shareholder, Stocks/Bonds (Private Company)

Gavin CKW Koh, PhD: AstraZeneca: Stocks/Bonds (Public Company); Generate:Biomedicines: Stocks/Bonds (Private Company); GlaxoSmithKline: Stocks/Bonds (Public Company)

Daria Hazuda, PhD: Generate Biomedicines: Stocks/Bonds (Private Company)

Francesco Borriello, MD PhD: No financial relationships to disclose